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Jai Ganesh
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Registered: 2005-06-28
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Nitrous Oxide

Nitrous Oxide

Gist

Nitrous oxide (N2O), commonly known as "laughing gas," is a colorless, slightly sweet-smelling non-flammable gas used extensively in medicine for sedation and pain relief, in dentistry, and in food production (whipped cream chargers). It is a powerful greenhouse gas and ozone-depleting substance.

Nitrous oxide has a pain-relieving and numbing effect, which is why it can be used as an anesthetic. It is also used in the chemicals industry and in farming. Nitrous oxide is absorbed into the blood through the lungs. It then enters the brain and nerve tissue through the bloodstream.

Summary

Nitrous oxide (dinitrogen oxide or dinitrogen monoxide), commonly known as laughing gas or nitrous, among others, is a chemical compound, an oxide of nitrogen with the formula N2O. At room temperature, it is a colourless non-flammable gas, and has a slightly sweet scent and taste. At elevated temperatures, nitrous oxide is a powerful oxidiser similar to molecular oxygen.

Nitrous oxide has significant medical uses, especially in surgery and dentistry, for its anaesthetic and pain-reducing effects, and it is on the World Health Organization's List of Essential Medicines. Its colloquial name, "laughing gas", coined by Humphry Davy, describes the euphoric effects upon inhaling it, which cause it to be used as a recreational drug inducing a brief "high". When abused chronically, it may cause neurological damage through inactivation of vitamin B12. It is also used as an oxidiser in rocket propellants and motor racing fuels, and as a frothing gas for whipped cream.

Nitrous oxide is also an atmospheric pollutant, with a concentration of 333 parts per billion (ppb) in 2020, increasing at 1 ppb annually. It is a major scavenger of stratospheric ozone, with an impact comparable to that of CFCs. About 40% of human-caused emissions are from agriculture, as nitrogen fertilisers are digested into nitrous oxide by soil micro-organisms. As the third most important greenhouse gas, nitrous oxide substantially contributes to global warming. Reduction of emissions is an important goal in the politics of climate change.

Details

Nitrous oxide (laughing gas) is a sedative healthcare providers use to keep you comfortable during procedures. It’s a colorless, faintly sweet-smelling gas that you breathe in through a nosepiece. Unlike other sedation options, you can drive shortly after receiving nitrous oxide.

Overview:

What is nitrous oxide (laughing gas)?

Nitrous oxide (N20) — commonly known as laughing gas — is a type of short-acting sedative. It’s a colorless, slightly sweet-smelling gas that you breathe in through a mask or nosepiece.

Physicians and dentists have been using nitrous oxide since the mid-19th century — and it’s still one of the most common inhaled sedatives used today. It’s fast-acting and it wears off quickly, making it an ideal sedation option for short or minor procedures.

What does laughing gas do?

Nitrous oxide slows down your nervous system and induces a sense of calm and euphoria. It reduces anxiety and helps you stay comfortable during medical or dental procedures. It doesn’t fully put you to sleep, so you’ll still be able to respond to your provider’s questions or instructions.

Despite its name, laughing gas might not make you laugh. (But then again, it could.) Everyone responds a little differently.

Nitrous oxide takes effect quickly. Within three to five minutes, you might feel:

* Calm.
* Relaxed.
* Happy.
* Giggly.
* Mildly euphoric.
* Light-headed.
* Tingling in your arms and legs.
* Heaviness, like you’re sinking deeper into the exam chair or table.

Who shouldn’t use nitrous oxide sedation?

Laughing gas is a safe medical and dental sedation option for most people, from children to adults. But it might not be right for kids under the age of 2 and those with:

* Certain respiratory conditions, like chronic obstructive pulmonary disease (COPD).
* Stuffy nose (nasal congestion).
* Vitamin B12 deficiency.
* Severe psychiatric conditions.

Ask your healthcare provider whether you’re a candidate for nitrous oxide sedation.

Treatment Details:

What should I expect if I’m getting laughing gas?

Your healthcare provider will talk with you and answer any questions before your procedure. They’ll ask you to sign a consent form so you can receive nitrous oxide.

When it’s time for your procedure, your provider will:

* Place a mask over your nose and mouth. (If you’re getting laughing gas at your dentist’s office, they’ll give you a smaller mask that only covers your nose.)
* Open a tank valve to allow nitrous oxide and oxygen to flow into your mask. (They’ll start with a very low dose to see how you respond.)
* Adjust the dosage until you feel the desired effects.
* Do your procedure. (In many cases, your provider will also give you local anesthesia before beginning. This is because nitrous oxide reduces pain but won’t totally eliminate it. So, it’s common to combine it with other forms of anesthesia.)
* Stop the flow of laughing gas once your procedure is over.
* Ask you to breathe in pure oxygen through your mask until you feel alert again.
* Remove the mask from your face.
* Monitor you for a few minutes before releasing you to go home.

It’s normal to feel a little nervous if you’ve never had laughing gas before. The good news is that you’ll be able to tell your provider if you develop undesirable side effects. If you start to feel dizzy or nauseous, your provider can simply adjust the dosage until it feels comfortable to you.

How long does laughing gas last?

The effects of nitrous oxide last until your provider turns off the gas flow. Once this happens, it takes about 5 to 10 minutes for the sedative to leave your system and for your headspace to return to normal. Due to the short-acting nature of nitrous oxide, you can drive shortly after your procedure.

Risks / Benefits:

What are the benefits of nitrous oxide?

The most notable advantage of laughing gas is that it relieves anxiety. People with medical- or dental-related fears often avoid healthcare visits and put off necessary procedures. Nitrous oxide makes it possible for people to get the care they need and deserve.

Nitrous oxide is also:

* Fast-acting (the effects kick in quickly).
* Short-acting. (Once your provider turns off the gas flow, you’ll start feeling like your usual self in a matter of minutes. This can be helpful if you find the effects of nitrous oxide unpleasant.)
* Easy to administer and doesn’t require needles.
* Safe and effective when given in a healthcare setting.

What are the possible complications of nitrous oxide in a dental or medical setting?

Laughing gas doesn’t cause any long-term complications when given under the care of a healthcare provider. But frequent nitrous oxide exposure (for multiple-phase dental treatment, for instance) can result in vitamin B12 deficiency. If you’re planning several appointments with laughing gas, ask your provider whether you should take a vitamin B12 supplement.

Some people may develop temporary nitrous oxide side effects like:

* Headaches.
* Nausea and vomiting.
* Agitation.

These side effects go away once the nitrous oxide leaves your system.

What are the risks of using nitrous oxide recreationally?

Some people use nitrous oxide recreationally to achieve a momentary euphoric high. But inhaling laughing gas more often than you need it can cause serious and potentially life-threatening health complications like:

* Low blood pressure (hypotension).
* Low oxygen (hypoxia).
* Fainting.
* Heart attack.
* Nerve damage.

People who use laughing gas recreationally have an increased risk of these long-term health conditions:

* Depression.
* Psychosis.
* Memory loss.
* Muscle spasms.
* Tinnitus (ringing in your ears).
* Numbness, especially in your hands and feet.
* Weakened immune system.
* Birth defects (if used during pregnancy).

Additional Information

Nitrous oxide (N2O) is any one of several oxides of nitrogen, a colourless gas with pleasant, sweetish odour and taste, which when inhaled produces insensibility to pain preceded by mild hysteria, sometimes laughter. (Because inhalation of small amounts provides a brief euphoric effect and nitrous oxide is not illegal to possess, the substance has been used as a recreational drug.) Nitrous oxide was discovered by the English chemist Joseph Priestley in 1772; another English chemist, Humphry Davy, later named it and showed its physiological effect. A principal use of nitrous oxide is as an anesthetic in surgical operations of short duration; prolonged inhalation causes death. The gas is also used as a propellant in food aerosols. In automobile racing, nitrous oxide is injected into an engine’s air intake; the extra oxygen allows the engine to burn more fuel per stroke. It is prepared by the action of zinc on dilute nitric acid, by the action of hydroxylamine hydrochloride (NH2OH·HCl) on sodium nitrite (NaNO2), and, most commonly, by the decomposition of ammonium nitrate (NH4NO3).

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