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2414) Rudolf Mössbauer
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According to the principles of quantum physics, the atomic nucleus and surrounding electrons can have only fixed energy levels. When there are transitions among energy levels in the atomic nucleus, high-energy photons known as gamma rays are emitted and absorbed. In a gas a recoil effect occurs when an atom emits a photon. In 1958 Rudolf Mössbauer discovered that the recoil can be eliminated if the atoms are embedded in a crystal structure. This opened up opportunities to study energy levels in atomic nuclei and how these are affected by their surroundings and various phenomena.
Summary
Rudolf Ludwig Mössbauer (born January 31, 1929, Munich, Germany—died September 14, 2011, Grünwald) was a German physicist and winner, with Robert Hofstadter of the United States, of the Nobel Prize for Physics in 1961 for his discovery of the Mössbauer effect.
Mössbauer discovered the effect in 1957, one year before he received his doctorate from the Technical University in Munich. Under normal conditions, atomic nuclei recoil when they emit gamma rays, and the wavelength of the emission varies with the amount of recoil. Mössbauer found that at a low temperature a nucleus can be embedded in a crystal lattice that absorbs its recoil. The discovery of the Mössbauer effect made it possible to produce gamma rays at specific wavelengths, and this proved a useful tool because of the highly precise measurements it allowed. The sharply defined gamma rays of the Mössbauer effect have been used to verify Albert Einstein’s general theory of relativity and to measure the magnetic fields of atomic nuclei.
Mössbauer became professor of physics at the California Institute of Technology, Pasadena, in 1961. Three years later he returned to Munich to become professor of physics at the Technical University, where he retired as professor emeritus in 1997.
Details
Rudolf Ludwig Mössbauer (31 January 1929 – 14 September 2011) was a German physicist who shared the 1961 Nobel Prize in Physics with Robert Hofstadter for his discovery of the Mössbauer effect, which is the basis for Mössbauer spectroscopy.
Career
Mössbauer was born in Munich, where he also studied physics at the Technical University of Munich. He prepared his Diplom thesis in the Laboratory of Applied Physics of Heinz Maier-Leibnitz and graduated in 1955. He then went to the Max Planck Institute for Medical Research in Heidelberg. Since this institute, not part of a university, had no right to award a doctorate, Mössbauer remained under the auspices of Maier-Leibnitz, his official thesis advisor, when he passed his PhD exam in Munich in 1958.
In his PhD, he discovered the recoilless nuclear fluorescence of gamma rays in 191 iridium, the Mössbauer effect. His fame grew immensely in 1960 when Robert Pound and Glen Rebka used this effect to prove the red shift of gamma radiation in the gravitational field of the Earth; this Pound–Rebka experiment was one of the first experimental precision tests of Albert Einstein's general theory of relativity. However, the long-term importance of the Mössbauer effect is its use in Mössbauer spectroscopy. Along with Robert Hofstadter, Rudolf Mössbauer was awarded the 1961 Nobel Prize in Physics.
On the suggestion of Richard Feynman, Mössbauer was invited in 1960 to Caltech in the USA, where he advanced rapidly from research fellow to senior research fellow; he was appointed a full professor of physics in early 1962. In 1964, his alma mater, the Technical University of Munich (TUM), convinced him to go back as a full professor. He retained this position until he became professor emeritus in 1997. As a condition for his return, the faculty of physics introduced a "department" system. This system, strongly influenced by Mössbauer's American experience, was in radical contrast to the traditional, hierarchical "faculty" system of German universities, and it gave the TUM an eminent position in German physics.
In 1972, Rudolf Mössbauer went to Grenoble to succeed Heinz Maier-Leibnitz as the director of the Institut Laue-Langevin just when its newly built high-flux research reactor went into operation. After serving a five-year term, Mössbauer returned to Munich, where he found his institutional reforms reversed by overarching legislation. Until the end of his career, he often expressed bitterness over this "destruction of the department." Meanwhile, his research interests shifted to neutrino physics.
Mössbauer was regarded as an excellent teacher. He gave highly specialized lectures on numerous courses, including Neutrino Physics, Neutrino Oscillations, The Unification of the Electromagnetic and Weak Interactions and The Interaction of Photons and Neutrons With Matter. In 1984, he gave undergraduate lectures to 350 people taking the physics course. He told his students: “Explain it! The most important thing is that you can explain it! You will have exams, there you have to explain it. Eventually, you pass them, you get your diploma and you think, that's it! – No, the whole life is an exam, you'll have to write applications, you'll have to discuss with peers... So learn to explain it! You can train this by explaining to another student, a colleague. If they are not available, explain it to your mother – or to your cat!”
Personal life
Mössbauer married Elizabeth Pritz in 1957. They had a son, Peter and two daughters Regine and Susi. They divorced in 1983, and he married his second wife Christel Braun in 1985.
Mössbauer died at Grünwald, Germany on 14 September 2011 at 82.

It appears to me that if one wants to make progress in mathematics, one should study the masters and not the pupils. - Niels Henrik Abel.
Nothing is better than reading and gaining more and more knowledge - Stephen William Hawking.
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2415) Melvin Calvin
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Work
One of the most fundamental processes of life is photosynthesis. Green plants use energy from sunlight to make carbohydrates out of water and carbon dioxide in the air. Through studies during the early 1950s, particularly of single-cell green algae, Melvin Calvin and his colleagues traced the path taken by carbon through different stages of photosynthesis. For this they made use of tools such as radioactive isotopes and chromatography. Their findings included insight into the important role played by phosphorous compounds during the composition of carbohydrates.
Summary
Melvin Ellis Calvin (April 8, 1911 – January 8, 1997) was an American biochemist known for discovering the Calvin cycle along with Andrew Benson and James Bassham, for which he was awarded the 1961 Nobel Prize in Chemistry. He spent most of his five-decade career at the University of California, Berkeley.
Early life and education
Melvin Calvin was born in St. Paul, Minnesota, the son of Elias Calvin and Rose Herwitz, Jewish immigrants from the Russian Empire (now known as Lithuania and Georgia).
At an early age, Melvin Calvin’s family moved to Detroit, Michigan where his parents ran a grocery store to earn their living. Melvin Calvin was often found exploring his curiosity by looking through all of the products that made up their shelves.
After he graduated from Central High School in 1928, he went on to study at Michigan College of Mining and Technology (now known as Michigan Technological University) where he received the school’s first Bachelors of Science in Chemistry. He went on to earn his PhD at the University of Minnesota in 1935. While under the mentorship of George Glocker, he studied and wrote his thesis on the electron affinity of halogens. He was invited to join the lab of Michael Polanyi as a Post Doctoral student at the University of Manchester. The two years he spent at the lab were focused on studying the structure and behavior of organic molecules. In 1942, He married Marie Genevieve Jemtegaard, and they had three daughters, Elin, Sowie, and Karole, and a son, Noel.
Career
On a visit to the University of Manchester, Joel Hildebrand, the director of UC Radiation Laboratory, invited Calvin to join the faculty at the University of California, Berkeley. This made him the first non-Berkeley graduate hired by the chemistry department in +25 years. He invited Calvin to push forward in radioactive carbon research because "now was the time". Calvin's original research at UC Berkeley was based on the discoveries of Martin Kamen and Sam Ruben in long-lived radioactive carbon-14 in 1940.
In 1947, he was promoted to a Professor of Chemistry and the director of the Bio-Organic Chemistry group in the Lawrence Radiation Laboratory. The team he formed included: Andrew Benson, James A. Bassham, and several others. Andrew Benson was tasked with setting up the photosynthesis laboratory. The purpose of this lab was to discover the path of carbon fixation through the process of photosynthesis. The greatest impact of the research was discovering the way that light energy converts into chemical energy. Using the carbon-14 isotope as a tracer, Calvin, Andrew Benson and James Bassham mapped the complete route that carbon travels through a plant during photosynthesis, starting from its absorption as atmospheric carbon dioxide to its conversion into carbohydrates and other organic compounds. The process is part of the photosynthesis cycle. It was given the name the Calvin–Benson–Bassham Cycle, named for the work of Melvin Calvin, Andrew Benson, and James Bassham. There were many people who contributed to this discovery but ultimately Melvin Calvin led the charge.
In 1963, Calvin was given the additional title of Professor of Molecular Biology. He was founder and Director of the Laboratory of Chemical Biodynamics, known as the “Roundhouse”, and simultaneously Associate Director of Berkeley Radiation Laboratory, where he conducted much of his research until his retirement in 1980. In his final years of active research, he studied the use of oil-producing plants as renewable sources of energy. He also spent many years testing the chemical evolution of life and wrote a book on the subject that was published in 1969.
Details
Melvin Calvin (born April 8, 1911, St. Paul, Minnesota, U.S.—died January 8, 1997, Berkeley, California) was an American biochemist who received the 1961 Nobel Prize for Chemistry for his discovery of the chemical pathways of photosynthesis.
Calvin was the son of immigrant parents. His father was from Kalvaria, Lithuania, so the Ellis Island immigration authorities renamed him Calvin; his mother was from Russian Georgia. Soon after his birth, the family moved to Detroit, Michigan, where Calvin showed an early interest in science, especially chemistry and physics. In 1927 he received a full scholarship from the Michigan College of Mining and Technology (now Michigan Technological University) in Houghton, where he was the school’s first chemistry major. Few chemistry courses were offered, so he enrolled in mineralogy, geology, paleontology, and civil engineering courses, all of which proved useful in his later interdisciplinary scientific research. Following his sophomore year, he interrupted his studies for a year, earning money as an analyst in a brass factory.
Calvin earned a bachelor’s degree in 1931, and then he attended the University of Minnesota in Minneapolis, from which he received a doctorate in 1935 with a dissertation on the electron affinity of halogen atoms. With a Rockefeller Foundation grant, he researched coordination catalysis, activation of molecular hydrogen, and metalloporphyrins (porphyrin and metal compounds) at the University of Manchester in England with Michael Polanyi, who introduced him to the interdisciplinary approach. In 1937 Calvin joined the faculty of the University of California, Berkeley, as an instructor. (He was the first chemist trained elsewhere to be hired by the school since 1912.) He rose through the ranks to become director (1946) of the bioorganic chemistry group at the school’s Lawrence Radiation Laboratory (now the Lawrence Livermore National Laboratory), director of the Laboratory of Chemical Biodynamics (1963), associate director of Lawrence Livermore (1967), and University Professor of Chemistry (1971).
At Berkeley, Calvin continued his work on hydrogen activation and began work on the colour of organic compounds, leading him to study the electronic structure of organic molecules. In the early 1940s, he worked on molecular genetics, proposing that hydrogen bonding is involved in the stacking of nucleic acid bases in chromosomes. During World War II, he worked on cobalt complexes that bond reversibly with oxygen to produce an oxygen-generating apparatus for submarines or destroyers. In the Manhattan Project, he employed chelation and solvent extraction to isolate and purify plutonium from other fission products of uranium that had been irradiated. Although not developed in time for wartime use, his technique was later used for laboratory separations.
In 1942 Calvin married Genevieve Jemtegaard, with later Nobel chemistry laureate Glenn T. Seaborg as best man. The married couple collaborated on an interdisciplinary project to investigate the chemical factors in the Rh blood group system. Genevieve was a juvenile probation officer, but, according to Calvin’s autobiography, “she spent a great deal of time actually in the laboratory working with the antigenic material. This was her first chemical laboratory experience but not her last by any means.” Together they helped to determine the structure of one of the Rh antigens, which they named elinin for their daughter Elin. Following the oil embargo after the 1973 Arab-Israeli War, they sought suitable plants, e.g., genus Euphorbia, to convert solar energy to hydrocarbons for fuel, but the project failed to be economically feasible.
In 1946 Calvin began his Nobel prize-winning work on photosynthesis. After adding carbon dioxide with trace amounts of radioactive carbon-14 to an illuminated suspension of the single-cell green alga Chlorella pyrenoidosa, he stopped the alga’s growth at different stages and used paper chromatography to isolate and identify the minute quantities of radioactive compounds. This enabled him to identify most of the chemical reactions in the intermediate steps of photosynthesis—the process in which carbon dioxide is converted into carbohydrates. He discovered the “Calvin cycle,” in which the “dark” photosynthetic reactions are impelled by compounds produced in the “light” reactions that occur on absorption of light by chlorophyll to yield oxygen. Also using isotopic tracer techniques, he followed the path of oxygen in photosynthesis. This was the first use of a carbon-14 tracer to explain a chemical pathway.
Calvin’s research also included work on electronic, photoelectronic, and photochemical behaviour of porphyrins; chemical evolution and organic geochemistry, including organic constituents of lunar rocks for the U.S. National Aeronautics and Space Administration (NASA); free radical reactions; the effect of deuterium (“heavy hydrogen”) on biochemical reactions; chemical and viral carcinogenesis; artificial photosynthesis (“synthetic chloroplasts”); radiation chemistry; the biochemistry of learning; brain chemistry; philosophy of science; and processes leading to the origin of life.
Calvin’s bioorganic group eventually required more space, so he designed the new Laboratory of Chemical Biodynamics (the “Roundhouse” or “Calvin Carousel”). This circular building contained open laboratories and numerous windows but few walls to encourage the interdisciplinary interaction that he had carried out with his photosynthesis group at the old Radiation Laboratory. He directed this laboratory until his mandatory age retirement in 1980, when it was renamed the Melvin Calvin Laboratory. Although officially retired, he continued to come to his office until 1996 to work with a small research group.
Calvin was the author of more than 600 articles and 7 books, and he was the recipient of several honorary degrees from U.S. and foreign universities. His numerous awards included the Priestley Medal (1978), the American Chemical Society’s highest award, and the U.S. National Medal of Science (1989), the highest U.S. civilian scientific award.

It appears to me that if one wants to make progress in mathematics, one should study the masters and not the pupils. - Niels Henrik Abel.
Nothing is better than reading and gaining more and more knowledge - Stephen William Hawking.
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2416) Georg von Békésy
Gist:
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Our hearing works because sound waves from the surrounding world are converted in the ear into vibrations in membranes and bones. These are further converted into electrical impulses that are passed on to the brain, resulting in auditory impressions. In a series of studies from 1940 to the 1960s, Georg von Békésy clarified how processes in the cochlea in the inner ear proceed, in part by studying vibrations in membranes with the help of a microscope and sequences of photographs as well as by measuring variations in electrical charges in the receptors.
Summary
Georg von Békésy (born June 3, 1899, Budapest, Hungary—died June 13, 1972, Honolulu, Hawaii, U.S.) was an American physicist and physiologist who received the 1961 Nobel Prize for Physiology or Medicine for his discovery of the physical means by which sound is analyzed and communicated in the cochlea, a portion of the inner ear.
As director of the Hungarian Telephone System Research Laboratory (1923–46), Békésy worked on problems of long-distance communication and became interested in the mechanics of human hearing. At the telephone laboratory, the University of Budapest (1939–46), the Karolinska Institute, Stockholm (1946–47), and Harvard University (1947–66) he conducted intensive research that led to the construction of two cochlea models and highly sensitive instruments that made it possible to understand the hearing process, differentiate between certain forms of deafness, and select proper treatment more accurately.
Since the mid-19th century, it had been known that the vibratory tissue most important for hearing is the basilar membrane, stretching the length of the snail-shaped cochlea and dividing it into two interior canals. Békésy found that sound travels along the basilar membrane in a series of waves, and he demonstrated that these waves peak at different places on the membrane: low frequencies toward the end of the cochlea and high frequencies near its entrance, or base. He discovered that the location of the nerve receptors and the number of receptors involved are the most important factors in determining pitch and loudness.
Békésy became professor of sensory sciences at the University of Hawaii in 1966. His books include Experiments in Hearing (1960) and Sensory Inhibition (1967).
Details
Georg von Békésy (3 June 1899 – 13 June 1972) was a Hungarian-American biophysicist.
By using strobe photography and silver flakes as a marker, he was able to observe that the basilar membrane moves like a surface wave when stimulated by sound. Because of the structure of the cochlea and the basilar membrane, different frequencies of sound cause the maximum amplitudes of the waves to occur at different places on the basilar membrane along the coil of the cochlea. High frequencies cause more vibration at the base of the cochlea while low frequencies create more vibration at the apex.
He concluded that his observations showed how different sound wave frequencies are locally dispersed before exciting different nerve fibers that lead from the cochlea to the brain.
In 1961, he was awarded the Nobel Prize in Physiology or Medicine for his research on the function of the cochlea in the mammalian hearing organ.
Biography
Békésy was born on 3 June 1899 in Budapest, Hungary, as the first of three children (György 1899, Lola 1901 and Miklós 1903) to Sándor Békésy (1860–1923), an economic diplomat, and to his mother Paula Mazaly.
The Békésy family was originally Reformed but converted to Catholicism. His mother, Paula Mazaly (1877–1974) was born in Szagolyca (now Čađavica, Croatia). His maternal grandfather was from Pécs. His father was born in Kolozsvár (now Cluj-Napoca, Romania).
Békésy went to school in Budapest, Munich, and Zürich. He studied chemistry in Bern and received his PhD in physics on the subject: "Fast way of determining molecular weight" from the University of Budapest in 1926.
He then spent one year working in an engineering firm. He published his first paper on the pattern of vibrations of the inner ear in 1928. He was offered a position at Uppsala University by Róbert Bárány, which he declined because of the hard Swedish winters.
Before and during World War II, Békésy worked for the Hungarian Post Office (1923 to 1946), where he did research on telecommunications signal quality. This research led him to become interested in the workings of the ear. In 1946, he left Hungary to follow this line of research at the Karolinska Institute in Sweden.
In 1947, he moved to the United States, working at Harvard University until 1966. In 1962 he was elected a Member of the German Academy of Sciences Leopoldina. After his lab was destroyed by fire in 1965, he was invited to lead a research laboratory of sense organs in Honolulu, Hawaii. He became a professor at the University of Hawaiʻi in 1966 and died in Honolulu.
He became a well-known expert in Asian art. He had a large collection which he donated to the Nobel Foundation in Sweden. His brother, Dr. Miklós Békésy (1903-1980), stayed in Hungary and became a famous agrobiologist who was awarded the Kossuth Prize.
Research
Békésy contributed most notably to our understanding of the mechanism by which sound frequencies are registered in the inner ear. He developed a method for dissecting the inner ear of human cadavers while leaving the cochlea partly intact. By using strobe photography and silver flakes as a marker, he was able to observe that the basilar membrane moves like a surface wave when stimulated by sound. Because of the structure of the cochlea and the basilar membrane, different frequencies of sound cause the maximum amplitudes of the waves to occur at different places on the basilar membrane along the coil of the cochlea. High frequencies cause more vibration at the base of the cochlea while low frequencies create more vibration at the apex.
Békésy concluded from these observations that by exciting different locations on the basilar membrane different sound wave frequencies excite different nerve fibers that lead from the cochlea to the brain. He theorized that, due to its placement along the cochlea, each sensory cell (hair cell) responds maximally to a specific frequency of sound (the so-called tonotopy). Békésy later developed a mechanical model of the cochlea, which confirmed the concept of frequency dispersion by the basilar membrane in the mammalian cochlea.
In an article published posthumously in 1974, Békésy reviewed progress in the field, remarking "In time, I came to the conclusion that the dehydrated cats and the application of Fourier analysis to hearing problems became more and more a handicap for research in hearing," referring to the difficulties in getting animal preparations to behave as when alive, and the misleading common interpretations of Fourier analysis in hearing research.

It appears to me that if one wants to make progress in mathematics, one should study the masters and not the pupils. - Niels Henrik Abel.
Nothing is better than reading and gaining more and more knowledge - Stephen William Hawking.
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